Abstract

Abstract : Teeth, as a highly mineralized tissue, are constantly subjected to processes of demineralization and remineralization during the whole life. An advantage of dentin over enamel is the presence of a collagen based scaffold that provides an appropriate cell-free backbone for repair/regenerations by development of a biomineralisation strategy. Among newer Biomodification protocols, application of LASERS appears to be a promising adjunct to conventional chemical techniques with remineralizing agents such as Casein Phospho Peptide-Amorphous Calcium Phosphate (CPP-ACP), Beta Tricalcium Phosphate (b-TCP), Grape Seed Extract (GSE), and Silver Diamine Fluoride (SDF). Variable LASER parameters include tissue type, exposure time, wavelength, pulse length and output power. All the agents showed remineralization potential; however, SDF showed maximum remineralization values followed by GSE, CPP-ACP and B-TC; while application of Gallium-Aluminium-Arsenic/ Diode LASER (980nm); lead to morphological changes of dentin which intensified with increase in wattage power. Well-known synthetic agents, nature derived agents and also physical methods which are also categorized as collagen cross linking agents have shown to effectively interact with type I collagen, thereby leading to biomineralisation of the dentin. The biomodification of Dentin, is a novel approach to improve the biomechanical and biochemical properties of the tissue for preventive or reparative/restorative purposes.